Brian J., as is his wont, offers this suggestion to NASA, totally free of charge:
If it’s planning on a Martian mission but it’s concerned about the conditions in small enclosed spaces for long periods of time and the effect on a person, NASA should just recruit young Manhattanites who might even pay for the privilege of doubling the size of their apartments to 300 square feet.
As I believe I’ve mentioned once before, my single-car garage measures out at 290 square feet. I don’t think I’d particularly want to live there. (It does have hot and cold running water, unless it’s below zero outside, but there’s only a small space heater.)